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Through its print and online incarnations, science reaches an estimated worldwide readership of more than one million. In a year marked by unprecedented shifts in science, policy, and the global economy, one constant remains in the job market

But that’s not the only reason science has named lenacapavir its 2024 breakthrough of the year In a move that is amplifying fears of the politicization of science under president donald trump, the director of the national institutes of health has abruptly replaced the chief of nih’s environmental health institute with a close friend of vice president jd vance. A new understanding of the structure and function of hiv’s capsid protein, which lenacapavir targets.